Junior dos Santos talks title defense against Alistair Overeem
Junior dos Santos reflects on Alistair Overeem's fight with Brock Lesnar and looks forward to a title defense against the Dutch kickboxer according to tatame.com.
"I thought Brock would move forwards, I hoped more of him. But he told me on the octagon he felt the knees and kicks of Overeem and that he thought he broke his rib. I saw it and it was really red....He's completely right to retire since he doesn't feel fine when fighting anymore," dos Santos said.
Overeem is set to be the next challenger for dos Santos' UFC heavyweight title after he scored a TKO victory over Lesnar in the first round at UFC 141. Overeem certainly made it look easy in his UFC debut as he out-muscled Lesnar and punished him with devastating knees before finishing the fight with a leg kick to the liver. Despite the strong performance, dos Santos is not afraid of his challenger.
"Each fight is different and you gotta be prepared for your next opponent the best way you can. I got to the title with much effort and I'll do my best to remain as the champion. Overeem is a very strong fighter, but there's no easy fight when you're fighting a title fight. He's big, but he ain't two," dos Santos said.
It wasn't long ago when dos Santos debuted with the UFC in a similar fashion to Overeem when he KO'ed Fabricio Werdum at UFC 90. Thereafter, dos Santos won his next seven fights and captured the heavyweight title in his last bout against Cain Velasquez at UFC on Fox 1.
Dos Santos recently underwent a successful knee surgery to repair a?torn meniscus and no date has been set for the dos Santos vs. Overeem heavyweight title fight.
CHICAGO Different ingredients in marijuana appear to affect regions of the brain differently during brain processing functions involving responses to certain visual stimuli and tasks, according to a report in the January issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
Sagnik Bhattacharyya, M.B.B.S., M.D., Ph.D, at the Institute of Psychiatry, King's College in London, and colleagues studied 15 healthy men, who were occasional marijuana users, to examine the effects of ?9-tetrahydrocannabinol (?9-THC) and cannabidiol (CBD) on regional brain function during salience processing, which is how people perceive things around them.
The authors used functional MRI images to study each participant on three occasions after administration of ?9-THC, CBD or placebo. Study participants performed a visual oddball task of pressing buttons according to the direction arrows on a screen were pointing, as a measure of attentional salience processing.
"Pairwise comparisons revealed that ?9-THC significantly increased the severity of psychotic symptoms compared with placebo and CBD whereas there was no significant difference between the CBD and placebo conditions," the authors conclude.
?9-THC had a greater effect than placebo on reaction time to nonsalient relative to salient stimuli. This was associated with modulation of both prefrontal and striatal function by ?9-THC, augmenting (increasing) activation in the former region and attenuating (weakening) it in the latter.
"Moreover, in the present study, the magnitude of ?9-THC's effect on response times to nonsalient stimuli was correlated with its effect on activation in the right caudate, the region where the physiological effect of ?9-THC was linked to its induction of psychotic symptoms," the authors write.
They conclude that "collectively, these observations suggest that ?9-THC may increase the aberrant attribution of salience and induce psychotic symptoms through its effects on the striatum and lateral prefrontal cortex."
When the effects of CBD were contrasted with ?9-THC and placebo with respect to the visual task there was a "significant effect" in the left caudate with CBD augmenting (increasing) the response and ?9-THC attenuating (weakening) it.
"These effects suggest that CBD may also influence the effect of cannabis use on salience processing and hence psychotic symptoms by having an opposite effect, enhancing the appropriate response to salient stimuli," the authors wrote.
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(Arch of Gen Psychiatry. 2012;69[1]:27-36). Available pre-embargo to the media at www.jamamedia.org.)
Editor's Note: This work was supported by a Joint Medical Research Council/Priory Clinical research training fellowship from the Medical Research Council, United Kingdom, to Dr. Bhattacharyya and a grant from the Psychiatry Research Trust, United Kingdom. Jose Alexandre Crippa, M.D., Ph.D., is the recipient of a Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (Brazil) productivity fellowship. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Study evaluates effects of marijuana ingredients on brain functioning during visual stimuliPublic release date: 2-Jan-2012 [ | E-mail | Share ]
CHICAGO Different ingredients in marijuana appear to affect regions of the brain differently during brain processing functions involving responses to certain visual stimuli and tasks, according to a report in the January issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
Sagnik Bhattacharyya, M.B.B.S., M.D., Ph.D, at the Institute of Psychiatry, King's College in London, and colleagues studied 15 healthy men, who were occasional marijuana users, to examine the effects of ?9-tetrahydrocannabinol (?9-THC) and cannabidiol (CBD) on regional brain function during salience processing, which is how people perceive things around them.
The authors used functional MRI images to study each participant on three occasions after administration of ?9-THC, CBD or placebo. Study participants performed a visual oddball task of pressing buttons according to the direction arrows on a screen were pointing, as a measure of attentional salience processing.
"Pairwise comparisons revealed that ?9-THC significantly increased the severity of psychotic symptoms compared with placebo and CBD whereas there was no significant difference between the CBD and placebo conditions," the authors conclude.
?9-THC had a greater effect than placebo on reaction time to nonsalient relative to salient stimuli. This was associated with modulation of both prefrontal and striatal function by ?9-THC, augmenting (increasing) activation in the former region and attenuating (weakening) it in the latter.
"Moreover, in the present study, the magnitude of ?9-THC's effect on response times to nonsalient stimuli was correlated with its effect on activation in the right caudate, the region where the physiological effect of ?9-THC was linked to its induction of psychotic symptoms," the authors write.
They conclude that "collectively, these observations suggest that ?9-THC may increase the aberrant attribution of salience and induce psychotic symptoms through its effects on the striatum and lateral prefrontal cortex."
When the effects of CBD were contrasted with ?9-THC and placebo with respect to the visual task there was a "significant effect" in the left caudate with CBD augmenting (increasing) the response and ?9-THC attenuating (weakening) it.
"These effects suggest that CBD may also influence the effect of cannabis use on salience processing and hence psychotic symptoms by having an opposite effect, enhancing the appropriate response to salient stimuli," the authors wrote.
###
(Arch of Gen Psychiatry. 2012;69[1]:27-36). Available pre-embargo to the media at www.jamamedia.org.)
Editor's Note: This work was supported by a Joint Medical Research Council/Priory Clinical research training fellowship from the Medical Research Council, United Kingdom, to Dr. Bhattacharyya and a grant from the Psychiatry Research Trust, United Kingdom. Jose Alexandre Crippa, M.D., Ph.D., is the recipient of a Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (Brazil) productivity fellowship. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: he-www2.heraldstandard.com --- Sunday, January 01, 2012 NOTICE NOTICE IS HEREBY GIVEN that the North Union Township Municipal Services Authority shall hold heir Reorganization & Special Meeting on January 4, 2012 at 6:00 pm at the Authoritys office located at 6 South Station Road, Lemont Furnace, PA Lawrence McLaughlin Secretary ...
HAVANA (Reuters) ? Pope Benedict XVI will visit Cuba on March 26-28 and perform two open-air masses on the communist island as part of his upcoming trip to Mexico and Cuba, Roman Catholic Church officials said on Sunday.
The 84-year-old pontiff was to fly from Mexico and arrive in the eastern city of Santiago, where he will be met by President Raul Castro, and then go on to Havana on March 27.
He will perform masses in the main plazas -- both known as Revolution Square -- of the two cities and also visit Cuba's most famous religious icon, the statue of the Virgin of Charity in the town of El Cobre, the Church said.
The purpose of the papal visit is in part to celebrate the 400th anniversary of the discovery of the relic, said to have been found by three fishermen floating in a bay in eastern Cuba.
A replica of the statue on Friday completed a 16-month pilgrimage around the island that was the first such religious display since the 1950s and a signal of improved relations between the government and the Church, which were at odds for many years following the 1959 revolution.
Relations began to warm in the 1990s, a process that was aided by a 1998 visit by Pope John Paul II, and intensified in 2010 when the church brokered a deal with Castro to release political prisoners.
It was not known if Benedict would meet with Fidel Castro, 85, who ruled Cuba for 49 years before his brother Raul Castro, 80, succeeded him in 2008.
The elder Castro now seldom appears in public, but occasionally meets in private with visiting foreign leaders and writes columns about international affairs.
The pope will go to Mexico for three days starting on May 23 before going to Cuba, Mexico church officials said on Sunday.
(Reporting by Jeff Franks; Editing by Philip Barbara)
Dallas Cowboys cornerback Terence Newman (41) fails to catch New York Giants wide receiver Victor Cruz (80) as he runs down the sideline to score on a 74-yard touchdown pass during the first half of an NFL football game Sunday, Jan. 1, 2012, in East Rutherford, N.J. (AP Photo/Julio Cortez)
Dallas Cowboys cornerback Terence Newman (41) fails to catch New York Giants wide receiver Victor Cruz (80) as he runs down the sideline to score on a 74-yard touchdown pass during the first half of an NFL football game Sunday, Jan. 1, 2012, in East Rutherford, N.J. (AP Photo/Julio Cortez)
New York Giants defensive end Jason Pierre-Paul celebrates after sacking Dallas Cowboys quarterback Tony Romo during the first half of an NFL game Sunday, Jan. 1, 2012, in East Rutherford, N.J. (AP Photo/Julio Cortez)
New York Giants defensive end Jason Pierre-Paul sacks Dallas Cowboys quarterback Tony Romo during the first half of an NFL game Sunday, Jan. 1, 2012, in East Rutherford, N.J. (AP Photo/Julio Cortez)
EAST RUTHERFORD, N.J. (AP) ? Eli Manning and Victor Cruz made sure that the all-or-nothing game for the Giants was all New York and nothing but frustration for the Dallas Cowboys.
Manning threw three touchdown passes, including a momentum-grabbing 74-yarder to Cruz early, and the Giants claimed the final spot in the NFL playoffs, beating the Cowboys 31-14 on Sunday night to win the NFC East.
"I knew we were going to fight and keep playing until the end, I feel good about the way we're handling the ups and downs, and it comes down to finishing," Manning said after throwing for 346 yards and no interceptions.
New York (9-7) won three of its final four games for 65-year-old coach Tom Coughlin and earned a wild-card home game next Sunday against the Atlanta Falcons (10-6).
"We've had a lot of ups and down, but when our team needed it most we responded," said the up-and-coming Cruz, who has capped his team-record setting season with six catches for 178 yards. "We were able to keep level-headed when we were on the four-game skid."
The Cowboys (8-8) lost four of their final five games in their first full season under coach Jason Garrett.
Dallas was its own worst enemy with the season on the line. It missed tackles on all three of the Giants' three first-half touchdowns, failed to recover two fumbles within its grasp in the half and failed to convert on a Tony Romo sneak on fourth-and-1 at the Giants 10 while trailing 21-7.
"It's extremely painful and it's a damn shame," Cowboys owner Jerry Jones said. "We have a good team and I thought we would be going to the playoffs, but that didn't happen. We have to be able to take some of the good with the bad and move on. We did a lot of good things this year, but to point to one thing why this happened would be subjective. We're 8-8 and we have to be better than that."
Romo, who played with a bruised right hand, moved the Cowboys in the second half but all he could generate were touchdown passes of 34 and 6 yards to Laurent Robinson.
"You can't make excuses,' said Romo, who finished 29 of 37 for 289 yards and one interception. "Either you win or you go home. Give them credit for coming in here and being ready. This is not going to sit well with me or anyone else on this team. It should fuel the fire to come back, but right now, it hurts."
The shorter touchdown pass to Robinson got Dallas within a 21-14 with 10:15 to play, but Cruz, the second-year pro from nearby Paterson who has become a fan favorite with a big plays and salsa celebrations, came through again.
Cruz boxed-out cornerback Orlando Scandrick on 44-yard third-down jump-ball catch and caught another for 20 yards to set up a 28-yard Lawrence Tynes' field goal. Manning iced the game with a 4-yard TD pass to Hakeem Nicks with 3:41 to play.
Manning finished 24 of 33 as the Giants beat the Cowboys for the second time in four games and ended a regular season marked by inconsistency on a high note. Cruz, who set a single-season record for yards receiving, averaged 29.7 yards on the night, and of course, he did his touchdown salsa after the first score.
"He's unbelievable," Giants guard Chris Snee said. "He's so explosive. He's so quick, he just runs away from people. He unbelivable. I don't know what else to say about the guy."
The Giants defense sacked Romo six times, including twice by Osi Umenyiora who returned to the lineup for the first time since spraining an ankle late last month. Dallas' final possession ended with Romo being sacked by Justin Tuck and losing a fumble.
"We needed this win," Umenyiora said. "This is the biggest win we've been a part of for a while."
The Giants haven't won a playoff game since beating the-then unbeaten New England Patriots in the Super Bowl in 2008, and the one thing that is seemingly apparent is that this team is peaking.
Coming off a 29-14 win over the rival Jets last week in what might have been the Giants best game of the season, Coughlin's team put together another outstanding 30 minutes in jumping to a 21-0 halftime lead.
Cruz, who sparked the win over the Jets' with a team-record 99-yard touchdown, made another monster play on the Giants' second offensive series, turning a short pass into points.
Cruz caught a short square out, eluded a tackle by Terence Newman, turned the corner after getting a seal block from Nicks and outraced two defenders down the sideline in front of the Giants bench for a 7-0 lead.
Dallas went three-and-out but had a chance to get right back into the game when Will Blackmon muffed a punt at near his 30-yard line and Alan Ball failed to recover.
Manning made Dallas pay. Manning hit Nicks for 18 yards and Devin Thomas for 14 en route on a 68-yard yard drive that Bradshaw capped with his 5-yard run. Safety Abram Elam had a chance to tackle Bradshaw in the backfield and Bradshaw scooted into the end zone after he missed.
Manning had passes of 14 and 12 yards to rookie fullback Henry Hynoski in an 80-yard touchdown drive just before the half. Bradshaw, who had a 29-yard run early in the drive, broke a tackle by linebacker Bradie James in scoring on a 10-yard swing pass for a 21-0 lead.
The Giants had chances to put the game away in the third quarter. They moved to the Dallas 42 on the opening possession of the second half and elected to punt.
Romo then drove the Cowboys 94 yards with a no-huddle offense, hitting Robinson on a 34-yard go pattern down the right sideline on a play that cornerback Corey Webster was beaten.
An interception by safety Antrel Rolle gave New York the ball in Dallas territory but they failed to convert a fourth-and-1 at the Dallas 35 and the Cowboys came right back to cut the deficit to seven.
Notes: Cowboys G Kyle Kosier left the game with a knee injury and was replaced by Kevin Kowalski replaced him. ...Cowboys LB DeMarcus Ware had 1? sacks and finished the season with 19?. ...LB Sean Lee led the Cowboys with 11 tackles. ...LB Mike Boley had nine for the Giants. ...New York's other sacks were registered by Jason Pierre-Paul (16?), LB Jacquian Williams, Tuck and Chris Canty. ...Dallas was limited to 49 yards rushing on 16 carries.
Twitter / HAL 9000: Jonathan Ive is being knig ...Jonathan Ive is being knighted for coming up with the designs for the iMac, iPod, iPhone, iPad, Samsung Galaxy S, Galaxy TabIl y a environ 19 heuresvia web
The holidays for most people who read this site involve answering a cornucopia of tech support questions for their relatives. Honestly, I've watched friends field the most frustrating 45 minute IT department-level questions during holiday time with the family, which inevitably devolves into more of those types of conversations in between "Pass the gravy." These conversations will only increase in frequency as the average consumer wakes up to smartphones and the app economy. According to Flurry, nearly a quarter of a billion app downloads this year occurred on December 24th and again this Christmas Day, more than 2x any other day thus far, ever.
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The holidays for most people who read this site involve answering a cornucopia of tech support questions for their relatives. Honestly, I've watched friends field the most frustrating 45 minute IT department-level questions during holiday time with the family, which inevitably devolves into more of those types of conversations in between "Pass the gravy." These conversations will only increase in frequency as the average consumer wakes up to smartphones and the app economy. According to